使用Word的COM组件。
Word._Application app = new Word.ApplicationClass();
app.Visible = false;
object nothing = System.Reflection.Missing.Value;
object temp = Environment.CurrentDirectory + @"\resume.doc"; //文档模板
Word.Document doc = app.Documents.Open(ref temp,ref nothing,ref nothing,ref nothing,
ref nothing,ref nothing,ref nothing, ref nothing, ref nothing,
ref nothing,ref nothing,ref nothing,ref nothing,ref nothing,ref nothing,ref nothing);//打开模板
doc.Tables[1].Cell(1,2).Range.Text = ""; // 给单元格添加内容
//给单元格插入图片
doc.Tables[1].Cell(1,5).Range.InlineShapes.AddPicture(ImgPath,ref nothing,ref nothing,ref nothing);
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